Tryptophan converts into 5-Hydroxytryptophan (5HTP) in the body, subsequently 5HTP is more active and less is required in supplementation ie. l,000mg of Tryptophan is equal in activity to 100mg of 5HTP.
5-HTP is needed by the body to make the brain chemical serotonin, from the essential amino acid L-tryptophan. Serotonin appears to play significant roles in sleep, emotional moods, pain control, inflammation, intestinal peristalsis, and other body functions.
5-HTP is not present in significant amounts in food, however, L-tryptophan is found in most dietary proteins including meat, fish and dairy foods. 5-HTP levels are not significantly increased by eating more of these foods. Supplemental 5-HTP is naturally derived from the seeds of Griffonia simplicifolia, a West African medicinal plant.
What it does
- Depression & Anxiety: Disruptions in emotional well-being, including depression and anxiety, have been linked to serotonin imbalances in the brain.
- Inflammation control: People with fibromyalgia often have low serotonin levels in their blood. Supplements of 5-HTP may increase serotonin synthesis in these cases.
- Migraines: The cause of migraine headaches is related to abnormal serotonin function in blood vessels, and 5-HTP may help correct this abnormality.
- Insomnia: Insomnia has been associated with tryptophan deficiency in the tissues of the brain.
|Fibromyalgia||Tension Headache||Weight loss and obesity|
|Seasonal Affective disorder||Anxiety|
Do not use in pregnancy or when breastfeeding.
5-HTP should not be taken with antidepressants, weight-control drugs, other serotonin-modifying agents, tramadol, or substances known to cause liver damage, because in these cases 5-HTP may have excessive effects.
People with liver disease may not be able to regulate 5-HTP adequately and those suffering from auto-immune diseases such as scleroderma may be more sensitive than others to 5-HTP. Do not take 5-HTP without first consulting your doctor.