Acetyl-L-carnitine is similar in form to the amino acid L-carnitine and also has some similar functions, such as being involved in the metabolism of food into energy. The acetyl group that is part of acetyl-L-carnitine contributes to the production of the neurotransmitter acetylcholine, which is required for mental function.
Acetyl-L-carnitine is a molecule that is produced naturally in the brain, liver, and kidney, but as we age, levels tend to decline. It is also available as a dietary supplement.
What it does
- Enhances Brain Function: ALC is structurally similar to the most abundant neurotransmitter in the brain, acetyl-choline, which becomes poorly utilised in Alzheimer’s disease. It is thought that ALC may mimic acetyl-choline in the brains of Alzheimer’s patients. ALC may also act as an antioxidant in the brain, stabilise cell membranes, aid the removal of cellular waste and improve energy production in brain cells.
- Energy Enhancing: ALC is required to carry long chain fatty acids into the mitochondria, the energy-producing components of cells, so they can be metabolised into energy.
- Anti-ageing: Supplementation can help counteract the decline in mitochondrial function due to lower levels of ALC as we age.
- Cholesterol: Can help improve the ratio between HDL and LDL cholesterol, which is thought to be one of the most important factors in preventing cardiovascular disease.
- Heart Health: Fatty acids are the primary source of fuel for the heart. Carnitine is required for the transport of fatty acids into the mitochondria, where they are metabolised into energy and is crucial to the maintenance of heart health. Whilst ALC can be used for heart health, L-Carnitine is the preferred form for this purpose.
Potential Uses
| Atherosclerosis | Cholesterol | Age related cognitive decline |
| Alzheimers disease | Dementia | Fatty liver disease |
| Muscle weakness | Depression in the elderly | Male infertility |
ALC has been shown to have a number of potential health benefits, including:
- Improved brain function
- Increased energy levels
- Reduced inflammation
- Improved heart health
- Reduced risk of Alzheimer’s disease
- Reduced risk of Parkinson’s disease
- Improved mitochondrial function
- Improved athletic performance
- Reduced symptoms of anxiety and depression
What are food sources of Acetyl-L-carnitine?
Food sources of Carnitine, which is converted to ALC in the body:
| Beef | cod | avocado |
| pork | chicken | whole-wheat bread |
| milk | ice cream | asparagus |
However, it is difficult to get enough ALC from food alone. For this reason, many people take ALC supplements.
L Carnitine how to take?
The ideal way to take L-Carnitine is to follow the dosage instructions provided by a healthcare professional or as indicated on the product label. It’s commonly available in capsule or powder form, which can be taken with or without food, depending on personal preference.
How much L Carnitine per day?
The recommended daily dosage of L-Carnitine can vary based on individual factors such as age, weight, and specific health goals. Generally, dosages range from 500mg to 2000mg per day. Consulting a healthcare provider ensures that the dosage aligns with your unique needs.
Is Acetyl-L-Carnitine used for weight loss?
Acetyl-L-Carnitine has gained attention for its potential role in supporting weight management. While it’s not a standalone weight loss solution, it may enhance the body’s ability to convert fat into energy, making it a popular addition to weight loss regimens.
What are the negative side effects of Acetyl-L-Carnitine?
When used as directed, Acetyl-L-Carnitine is generally considered safe. However, some individuals may experience mild side effects like nausea or gastrointestinal discomfort. High doses may lead to insomnia or restlessness. Consulting a healthcare provider can help mitigate potential risks.
ALC is generally safe for most people to take. However, some people may experience side effects such as:
- Stomach upset
- Nausea
- Vomiting
- Diarrhea
- Headache
- Dizziness
- Restlessness
- Insomnia
When should you take Acetyl-L-Carnitine?
The timing of ALCAR intake largely depends on your health goals. Many individuals find benefit in taking it in the morning to support mental clarity and energy throughout the day. However, some prefer to split the dosage, taking it in the morning and again in the afternoon.
However, some people find that it is best to take ALC in the morning or early afternoon to avoid any sleep disturbances.
What happens when you take L-Carnitine everyday?
Consistent use of L-Carnitine, especially in its acetylated form, may lead to improved energy levels, enhanced cognitive function, and potentially support weight management efforts. Regular use allows the body to maintain a steady supply of this crucial compound. Although this acid is not in deficit in human body by default, so before determining how long to take it we recommend to contact a doctor for some exams and blood tests.
Is acetyl-L-carnitine safe for kidneys?
In general, Acetyl-L-Carnitine is considered safe for individuals with healthy kidney function. However, those with pre-existing kidney conditions should consult a healthcare professional before starting any supplementation regimen. Monitoring kidney function during supplementation is advisable.
How does acetyl L carnitine impact anxiety?
Acetyl-L-Carnitine shows promise in alleviating symptoms of anxiety. Some research suggests that ALC may help to reduce symptoms of anxiety. ALC may work by increasing levels of serotonin, a neurotransmitter that has calming effects. By supporting neurotransmitter function and energy production within brain cells, ALCAR may help regulate mood and reduce anxiety levels. However, individual responses may vary, and it’s important to consult a healthcare provider for personalized advice.
Cautions
Incorporating Acetyl-L-Carnitine into your health routine can be a valuable step towards enhancing both mental and physical well-being. Remember, consulting a healthcare professional for personalized advice tailored to your specific needs is always a wise choice.
ALC should be avoided if pregnant or breastfeeding unless under supervision by a qualified medical health practitioner.
Slight digestive discomfort and skin irritation may be experienced.
Carnitine deficiency may arise from use of various drugs, including valproic acid, phenobarbitol, didanosine, zalcitabine, stavudine, and pivalic acid containing antibiotics.
