Nicotinamide adenine dinucleotide (NADH) is the active coenzyme form of vitamin B3 (niacin). NADH deficiency is known to occur only in the presence of vitamin B3 deficiency, which is rare in Western society except in some alcoholics.
What it does
NADH plays an essential role in the energy production of every human cell. It is thought that some people may have difficulty converting Vitamin B3 to NADH making them prone to disorders which affect energy levels. There is some NADH in meat, fish and poultry but it is thought that it may not be well absorbed in sufficient quantity.
Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells. It plays a vital role in many cellular processes, including energy metabolism, DNA repair, and cell signaling. NAD+ levels decline with age, which is thought to contribute to age-related diseases such as Alzheimer’s disease, Parkinson’s disease, and cancer.
Benefits of NAD+
NAD+ has a number of potential health benefits, including:
- Boosting energy levels: NAD+ is essential for energy production in the cells. By increasing NAD+ levels, NAD+ boosters can help to improve energy levels and reduce fatigue.
- Improving cognitive function: NAD+ is involved in a number of processes that are important for cognitive function, such as memory formation and learning. NAD+ boosters have been shown to improve cognitive function in animal studies and in some human studies.
- Protecting against neurodegenerative diseases: NAD+ levels decline with age, and this decline is thought to contribute to the development of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. NAD+ boosters have been shown to protect against neurodegenerative diseases in animal studies.
- Reducing the risk of cancer: NAD+ is involved in a number of processes that can help to protect against cancer, such as DNA repair and cell death. NAD+ boosters have been shown to reduce the risk of cancer in animal studies.
- Extending lifespan: NAD+ levels decline with age, and this decline is thought to be a major factor in aging. NAD+ boosters have been shown to extend lifespan in animal studies.
Potential Uses
| Chronic fatigue syndrome | Alzheimer’s disease | Parkinson’s disease |
| Depression |
Consequences of NAD+ Deficiency
NAD+ deficiency can lead to a number of health problems, including:
- Fatigue: NAD+ is essential for energy production in the cells. NAD+ deficiency can lead to fatigue and weakness.
- Cognitive decline: NAD+ is involved in a number of processes that are important for cognitive function, such as memory formation and learning. NAD+ deficiency can lead to cognitive decline and dementia.
- Neurodegenerative diseases: NAD+ levels decline with age, and this decline is thought to contribute to the development of neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.
- Cancer: NAD+ is involved in a number of processes that can help to protect against cancer, such as DNA repair and cell death. NAD+ deficiency can increase the risk of cancer.
- Shortened lifespan: NAD+ levels decline with age, and this decline is thought to be a major factor in aging. NAD+ deficiency can lead to a shortened lifespan.
What is nicotinamide adenine dinucleotide used for?
NAD+ is used for a variety of things, including:
- Energy production
- DNA repair
- Cell signaling
- Gene expression
- Immune function
- Circadian rhythm regulation
What is the role of NAD?
NAD+ is a coenzyme that plays a vital role in many cellular processes. It acts as an electron carrier, helping to transfer electrons from one molecule to another. This is essential for energy production, DNA repair, and cell signaling.
Is NAD the same as vitamin B3?
No, NAD+ is not the same as vitamin B3. NAD+ is a coenzyme that is derived from vitamin B3, but it is not the same thing. Vitamin B3 is a nutrient that is essential for human health, while NAD+ is a coenzyme that is involved in many cellular processes.
What vitamin is NAD derived from?
NAD+ is derived from vitamin B3, also known as niacin. Niacin is a nutrient that is essential for human health. It is found in a variety of foods, including meat, poultry, fish, eggs, and dairy products.
NAD+ booster
An NAD+ booster is a substance that can help to increase NAD+ levels in the body. There are a number of different NAD+ boosters available, including:
- Nicotinamide riboside (NR): NR is a precursor to NAD+ that has been shown to increase NAD+ levels in animal studies and in some human studies.
- Nicotinamide mononucleotide (NMN): NMN is another precursor to NAD+ that has been shown to increase NAD+ levels in animal studies and in some human studies.
- Pterostilbene: Pterostilbene is a plant compound that has been shown to increase NAD+ levels in animal studies and in some human studies.
NAD+ boosters are a promising new approach to treating a variety of age-related diseases. However, more research is needed to confirm the safety and efficacy of NAD+ boosters in humans.
Cautions
At the time of writing there were no well known negative drug interactions with NADH.
Generally, there are no side effects or contra-indications from using NADH.
